Selected Publications


Clinical and laboratory features distinguishing MOG antibody disease from multiple sclerosis and AQP4 antibody-positive neuromyelitis optica.

John R Ciotti, Noah S Eby, Gregory F Wu, Robert T Naismith, Salim Chahin, Anne H Cross. Mult Scler Relat Disord. 2020 Oct;45:102399.

cDC1 prime and are licensed by CD4+ T cells to induce anti-tumour immunity.

Stephen T Ferris, Vivek Durai, Renee Wu, Derek J Theisen, Jeffrey P Ward, Michael D Bern, Jesse T Davidson 4th, Prachi Bagadia, Tiantian Liu, Carlos G BriseƱo, Lijin Li, William E Gillanders, Gregory F Wu, Wayne M Yokoyama, Theresa L Murphy, Robert D Schreiber, Kenneth M Murphy. Nature. 2020 Aug 12;584(7822):624-629.

Single-cell RNA-seq analysis of human CSF microglia and myeloid cells in neuroinflammation.

Ekaterina Esaulova, Claudia Cantoni, Irina Shchukina, Konstantin Zaitsev, Robert C Bucelli, Gregory F Wu, Maxim N Artyomov, Anne H Cross, Brian T Edelson. Neurol Neuroimmunol Neuroinflamm 2020 May 5;7(4):e732.

Neutrophils promote VLA-4-dependent B cell antigen presentation and accumulation within the meninges during neuroinflammation.

Parker Harp CR, Archambault AS, Cheung M, Williams JW, Czepielewski RS, Duncker PC, Kilgore AJ, Miller AT, Segal BM, Kim AHJ, Randolph GJ, Wu GF. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24221-24230.

X-tra X: An escape to autoimmunity.

Wu GF. J Clin Invest. 2019 Aug 12;130:3536-3538.

B Cell-Mediated Antigen Presentation through MHC Class II Is Dispensable for Atherosclerosis Progression.

Williams JW, Elvington A, Kessler S, Wohltmann M, Wu GF, Randolph GJ. Immunohorizons. 2019 Jan 21;3(1):37-44.

B cells are capable of independently eliciting rapid reactivation of encephalitogenic CD4 T cells in a murine model of multiple sclerosis.

Parker Harp CR, Archambault AS, Sim J, Shlomchik MJ, Russell JH, Wu GF. PLoS One. 2018 Jun 26;13(6):e0199694.

MicroRNA signature of central nervous system-infiltrating dendritic cells in an animal model of multiple sclerosis.

Hoye ML, Archambault AS, Gordon TM, Oetjen LK, Cain MD, Klein RS, Crosby SD, Kim BS, Miller TM, Wu GF. Immunology. 2018 Sep;155(1):112-122.

Role of B cells in TH cell responses in a mouse model of asthma.

Wypych TP, Marzi R, Wu GF, Lanzavecchia A, Sallusto F. J Allergy Clin Immunol. 2018 Apr;141(4):1395-1410.

Functional connectivity alterations in a murine model of optic neuritis.

Wright PW, Archambault AS, Peek S, Bauer AQ, Culican SM, Ances BM, Culver JP, Wu GF. Eep Neurol. 2017 May 11.pii: S0014-4886(17)30121-8.

Mir-223 regulates the number and function of myeloid-derived suppressor cells in multiple sclerosis and experimental autoimmune encephalomyelitis.

Cantoni C, Cignarella F, Ghezzi L, Mikesell B, Bollman B, Berrien-Elliott MM, Ireland AR, Fehniger TA, Wu GF, Piccio L. Acta Neuropathol. 2016 Oct 4.

IL-1-induced Bhlhe40 identifies pathogenic T helper cells in a model of autoimmune neuroinflammation.

Lin CC, Bradstreet TR, Schwarzkopf EA, Jarjour NN, Chou C, Archambault AS, Sim J, Zinselmeyer BH, Carrero JA, Wu GF, Taneja R, Artyomov MN, Russell JH, Edelson BT. J Exp Med. 2016 Feb 8;213(2):251-71. doi: 10.1084/jem.20150568.

B cell antigen presentation is sufficient to drive neuroinflammation in an animal model of multiple sclerosis.

Parker Harp CR, Archambault AS, Sim J, Ferris ST, Mikesell RJ, Koni PA, Shimoda M, Linington C, Russell JH, Wu GF. J Immunol. 2015 Jun 1;194(11):5077-84.

An Eye on Brain Integrity: Acute Optic Neuritis Affects Resting State Functional Connectivity.

Wu GF, Brier MR, Parks CA, Ances BM, Van Stavern GP. Invest Ophthalmol Vis Sci. 2015 Apr;56(4):2541-6.

RNA-sequencing reveals oligodendrocyte and neuronal transcripts in microglia relevant to central nervous system disease.

Solga AC, Pong WW, Walker J, Wylie T, Magrini V, Apicelli AJ, Griffith M, Griffith OL, Kohsaka S, Wu GF, Brody DL, Mardis ER, Gutmann DH. Glia. 2015 Apr;63(4):531-48.

Apolipoprotein E Mediation of Neuro-Inflammation in a Murine model of Multiple Sclerosis

Shin S, Walz KA, Archambault AS, Sim J, Bollman BP, Koenigsknecht-Talboo J, Cross AH, Holtzman DM, Wu GF. Apolipoprotein E Mediation of Neuro-Inflammation in a Murine Model of Multiple Sclerosis. J Neuroimmunol. 2014 Jun; 271(1-2): 8-17.

B Cell Antigen Presentation in the Initiation of Follicular Helper T Cell and Germinal Center Differentiation

Barnett LG, Simkins HM, Barnett BE, Korn LL, Johnson AL, Wherry EJ, Wu GF, Laufer TM. B Cell Antigen Presentation in the Initiation of Follicular Helper T Cell and Germinal Center Differentiation. J Immunol. 2014 Apr; 192(8): 3607-17.

Method for Widespread MicroRNA-155 Inhibition Prolongs Survival in ALS-Model Mice

Kovel ED, Shaner C, Zhang P, du Maine X, Fischer K, Tay J, Chau BN, Wu GF, Miller TM. Method for Widespread MicroRNA-155 Inhibition Prolongs Survival in ALS-Model Mice. Hum Mol Genet. 2013 Oct; 22(20): 4127-35.

Differential Targeting of IL-2 and T Cell Receptor Signalling Pathways Selectively Expands Regulatory T Cells while Inhibiting Conventional T Cells

Satake A, Schmidt AM, Achambault A, Leichner TM, Wu GF, Kambayashi T. Differential Targeting of IL-2 and T Cell Receptor Signalling Pathways Selectively Expands Regulatory T Cells while Inhibiting Conventional T Cells. J Autoimmun. 2013 Aug; 44: 13-20.

Cutting Edge: Conditional MHC Class II Expression Reveals a Limited Role for B Cell Antigen Presentation in Primary and Secondary CD4 T Cell Responses

Archambault AS, Carrero JA, Barnett LG, McGee NG, Sim J, Wright JO, Raabe T, Chen P, Ding H, Allenspach EJ, Dragatsis I, Laufer TM, Wu GF. Cutting Edge: Conditional MHC Class II Expression Reveals a Limited Role for B Cell Antigen Presentation in Primary and Secondary CD4 T Cell Responses. J Immunol. 2013 Jul; 191(12): 545-50